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5TYI

Grb7 SH2 with bicyclic peptide containing pY mimetic

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DGrowth factor receptor-bound protein 7polymer12013690.74UniProt (Q14451)
Pfam (PF00017)
In PDB
Homo sapiens (Human)B47,Epidermal growth factor receptor GRB-7,GRB7 adapter protein
2L, M, N, PPeptide inhibitorpolymer91190.24synthetic construct
3waterwater18.0122Chemie (HOH)
Sequence modifications
A, B, C, D: 415 - 532 (UniProt: Q14451)
PDBExternal DatabaseDetails
Gly 413-expression tag
Ser 414-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight59523.7
All*Total formula weight59523.7
*Water molecules are not included.

222415

PDB entries from 2024-07-10

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