5TXY
Identification of a New Zinc Binding Chemotype of by Fragment Screening on human carbonic anhydrase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
4 | A | (5R)-5-phenyl-1,3-oxazolidine-2,4-dione | non-polymer | 177.2 | 1 | Chemie (7Q1) | |||
5 | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29289.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 288.6 | |
All* | Total formula weight | 29577.7 |