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5TXR

Structure of ALAS from S. cerevisiae non-covalently bound to PLP cofactor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
5-aminolevulinate synthase, mitochondrialpolymer49153970.12UniProt (P09950)
Pfam (PF00155)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)5-aminolevulinic acid synthase,Delta-ALA synthase,Delta-aminolevulinate synthase
2C, D, E, F, J...
(B, A)
FORMIC ACIDnon-polymer46.010Chemie (FMT)
3G, P
(B, A)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.12Chemie (PLP)
4H
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5I
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
6Q, R
(B, A)
waterwater18.0775Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight107940.2
Non-Polymers*Number of molecules14
Total formula weight1085.7
All*Total formula weight109026.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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