5TXK
CRYSTAL STRUCTURE OF USP35 C450S IN COMPLEX WITH UBIQUITIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ubiquitin carboxyl-terminal hydrolase 35,Ubiquitin carboxyl-terminal hydrolase 35 | polymer | 372 | 41739.2 | 1 | UniProt (Q9P2H5) Pfam (PF00443) In PDB | Homo sapiens (Human) | Deubiquitinating enzyme 35,Ubiquitin thioesterase 35,Ubiquitin-specific-processing protease 35,Deubiquitinating enzyme 35,Ubiquitin thioesterase 35,Ubiquitin-specific-processing protease 35 |
| 2 | B | Polyubiquitin-B | polymer | 76 | 8576.8 | 1 | UniProt (J3QS39) Pfam (PF00240) UniProt (by SIFTS) (P0CG47) In PDB | Homo sapiens (Human) | |
| 3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | water | water | 18.0 | 683 | Chemie (HOH) |
Sequence modifications
A: 423 - 603 (UniProt: Q9P2H5)
A: 754 - 944 (UniProt: Q9P2H5)
| PDB | External Database | Details |
|---|---|---|
| Ser 450 | Cys 450 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50316.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 539.8 | |
| All* | Total formula weight | 50855.8 |
