Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0016579 | biological_process | protein deubiquitination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 1001 |
| Chain | Residue |
| A | ARG577 |
| A | SER588 |
| A | SER902 |
| A | PHE903 |
| A | GLU904 |
| A | HOH1184 |
| A | HOH1234 |
| A | HOH1348 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1002 |
| Chain | Residue |
| A | HOH1227 |
| A | HOH1319 |
| B | GLN40 |
| B | ARG74 |
| A | ARG820 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 1003 |
| Chain | Residue |
| A | PHE490 |
| A | SER494 |
| A | GLN495 |
| A | ARG496 |
| A | HOH1217 |
| A | HOH1295 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1004 |
| Chain | Residue |
| A | TYR864 |
| A | HOH1157 |
| A | HOH1212 |
| A | HOH1298 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1005 |
| Chain | Residue |
| A | GLU567 |
| A | GLY571 |
| A | THR594 |
| A | HOH1138 |
| A | HOH1144 |
| A | HOH1363 |
| B | HOH269 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1006 |
| Chain | Residue |
| A | CYS580 |
| A | CYS583 |
| A | CYS782 |
| A | CYS785 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 101 |
| Chain | Residue |
| A | TRP512 |
| A | GLN519 |
| B | ARG72 |
| B | ARG74 |
| B | HOH226 |
| B | HOH267 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 | |
| site_id | PS00973 |
| Number of Residues | 19 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YdLcSVvvHsGvsses.GHY |
| Chain | Residue | Details |
| A | TYR845-TYR863 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 75 |
| Details | Domain: {"description":"Ubiquitin-like 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]} |
