5TXI
Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Penicillin binding protein 4 | polymer | 359 | 40251.4 | 2 | UniProt (A0A0H2WY27) Pfam (PF00144) Pfam (PF00768) Pfam (PF09211) UniProt (by SIFTS) (Q2G2X6) In PDB | Staphylococcus aureus | |
| 2 | A, B | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | non-polymer | 536.6 | 2 | Chemie (RB6) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | A, B | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 7 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | water | water | 18.0 | 580 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80502.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1781.9 | |
| All* | Total formula weight | 82284.7 |
