5TX5
Rip1 Kinase ( flag 1-294, C34A, C127A, C233A, C240A) with GSK772
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Receptor-interacting serine/threonine-protein kinase 1 | polymer | 303 | 34596.9 | 2 | UniProt (Q13546) Pfam (PF07714) In PDB | Homo sapiens (Human) | Cell death protein RIP,Receptor-interacting protein 1,RIP-1,Serine/threonine-protein kinase RIP |
2 | A, B | 3-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-5-carboxamide | non-polymer | 377.4 | 2 | Chemie (7MJ) | |||
3 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 294 (UniProt: Q13546)
PDB | External Database | Details |
---|---|---|
Met -8 | - | initiating methionine |
Asp -7 | - | expression tag |
Tyr -6 | - | expression tag |
Lys -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Asp -1 | - | expression tag |
Lys 0 | - | expression tag |
Ala 34 | Cys 34 | engineered mutation |
Ala 127 | Cys 127 | engineered mutation |
Ala 233 | Cys 233 | engineered mutation |
Ala 240 | Cys 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 69193.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 754.8 | |
All* | Total formula weight | 69948.6 |