5TUS
Potent competitive inhibition of human ribonucleotide reductase by a novel non-nucleoside small molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribonucleoside-diphosphate reductase large subunit | polymer | 792 | 90179.0 | 2 | UniProt (P23921) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Homo sapiens (Human) | Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large subunit |
| 2 | C, E (A, B) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 2 | Chemie (TTP) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G (B) | 2-hydroxy-N'-[(Z)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide | non-polymer | 306.3 | 1 | Chemie (7LL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 180358.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1319.3 | |
| All* | Total formula weight | 181677.3 |
