5TQW
CryoEM reconstruction of human IKK1, open conformation 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Inhibitor of nuclear factor kappa-B kinase subunit alpha | polymer | 655 | 75146.9 | 2 | UniProt (O15111) Pfam (PF00069) Pfam (PF18397) In PDB | Homo sapiens (Human) | IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B inhibitor kinase alpha, NFKBIKA, Transcription factor 16, TCF-16 |
Sequence modifications
A, B: 10 - 660 (UniProt: O15111)
| PDB | External Database | Details |
|---|---|---|
| Asp 6 | - | expression tag |
| Pro 7 | - | expression tag |
| Glu 8 | - | expression tag |
| Phe 9 | - | expression tag |
| Glu 176 | Ser 176 | engineered mutation |
| Glu 180 | Ser 180 | engineered mutation |
| Ile 268 | Val 268 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 150293.9 | |
| All* | Total formula weight | 150293.9 |
