5TQE
Factor VIIa in complex with the inhibitor (5R)-5-[(1-aminoisoquinolin-6-yl)amino]-19-(cyclopropylsulfonyl)-3-methyl-13-oxa-3,15-diazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaene-4,14-dione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | Factor VIIa (Heavy Chain) | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA, ACTIVATED FACTOR VIIA HEAVY CHAIN |
| 2 | L | Factor VIIa (Light Chain) | polymer | 55 | 6030.8 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | H | (5R)-5-[(1-aminoisoquinolin-6-yl)amino]-19-(cyclopropylsulfonyl)-3-methyl-13-oxa-3,15-diazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaene-4,14-dione | non-polymer | 585.7 | 1 | Chemie (7KQ) | |||
| 4 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | H | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | H | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 368 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34134.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1286.3 | |
| All* | Total formula weight | 35420.4 |
