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5TQ0

Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NMDA glutamate receptor subunitpolymer39143801.01UniProt (Q91977)
Pfam (PF01094)
UniProt (by SIFTS) (A0A1L8F5J9)
Xenopus laevis (African clawed frog)
2B
(B)
Glutamate receptor ionotropic, NMDA 2Apolymer36040572.11UniProt (Q00959)
Pfam (PF01094)
Rattus norvegicus (Rat)GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NR2A
3C
(H)
FAB, HEAVY CHAINpolymer22123993.91Mus musculus (mouse)
4D
(L)
FAB, LIGHT CHAINpolymer21423568.01Mus musculus
5E, F
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
6G, H
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
7I, J, K, L, M...
(A, B, L)
SULFATE IONnon-polymer96.112Chemie (SO4)
8S
(H)
ISOPROPYL ALCOHOLnon-polymer60.11Chemie (IPA)
9V, W, X, Y
(A, B, H, L)
waterwater18.050Chemie (HOH)
Sequence modifications
A: 24 - 408 (UniProt: Q91977)
PDBExternal DatabaseDetails
Gln 61Asn 61engineered mutation
Gln 371Asn 371engineered mutation
Gly 409-expression tag
Thr 410-expression tag
Leu 411-expression tag
Val 412-expression tag
Pro 413-expression tag
Arg 414-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight131935.0
Non-Polymers*Number of molecules17
Total formula weight1839.5
All*Total formula weight133774.5
*Water molecules are not included.

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PDB entries from 2025-07-02

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