5TPX

Bromodomain from Plasmodium Faciparum Gcn5, complexed with compound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Histone acetyltransferase GCN5	polymer	123	14765.8	1	UniProt (Q8IB67)	Plasmodium falciparum (isolate 3D7)
2	B (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	C, D, E (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	F (A)	(1S,2S)-N~1~,N~1~-dimethyl-N~2~-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-1-phenylpropane-1,2-diamine	non-polymer		360.5	1	Chemie (7H7)
5	G (A)	water	water		18.0	66	Chemie (HOH)

Sequence modifications

A: 1356 - 1460 (UniProt: Q8IB67)

PDB	External Database	Details
Met 1338	-	initiating methionine
His 1339	-	expression tag
His 1340	-	expression tag
His 1341	-	expression tag
His 1342	-	expression tag
His 1343	-	expression tag
His 1344	-	expression tag
Ser 1345	-	expression tag
Ser 1346	-	expression tag
Gly 1347	-	expression tag
Arg 1348	-	expression tag
Glu 1349	-	expression tag
Asn 1350	-	expression tag
Leu 1351	-	expression tag
Tyr 1352	-	expression tag
Phe 1353	-	expression tag
Gln 1354	-	expression tag
Gly 1355	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14765.8
Non-Polymers*	Number of molecules	5
	Total formula weight	684.1
All*	Total formula weight	15449.9

*Water molecules are not included.