5TOW
Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in ternary complex with NADH and Adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Adenosylhomocysteinase | polymer | 407 | 45178.8 | 2 | UniProt (O51933) Pfam (PF05221) Pfam (PF00670) | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | S-adenosyl-L-homocysteine hydrolase,AdoHcyase |
| 2 | C (A) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 3 | D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | E (B) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (928) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (11250888) PubChem (129607000) PubChem (129628338) PubChem (12309341) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 5 | F, G (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 581 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 404 (UniProt: O51933)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90357.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1121.8 | |
| All* | Total formula weight | 91479.5 |
