5TKM

Crystal structure of human APOBEC3B N-terminal Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA dC->dU-editing enzyme APOBEC-3B	polymer	198	23583.7	2	UniProt (Q9UH17) Pfam (PF18782)	Homo sapiens (Human)	A3B,Phorbolin-1-related protein,Phorbolin-2/3
2	C, D (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	E, F (A, B)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A, B: 1 - 191 (UniProt: Q9UH17)

PDB	External Database	Details
Gly -6	-	expression tag
Pro -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Asp 13	Tyr 13	engineered mutation
Ser 28	Tyr 28	engineered mutation
Asp 83	Tyr 83	engineered mutation
Ser 127	Trp 127	engineered mutation
Lys 146	Thr 146	engineered mutation
Asp 162	Tyr 162	engineered mutation
His 191	Tyr 191	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47167.5
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	47298.3

*Water molecules are not included.