5TJY
Structure of 4-Hydroxy-tetrahydrodipicolinate Reductase from Mycobacterium tuberculosis with 2,6 Pyridine Dicarboxylic Acid and NADH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 4-hydroxy-tetrahydrodipicolinate reductase | polymer | 245 | 25682.3 | 1 | UniProt (A5U6C6) Pfam (PF01113) Pfam (PF05173) | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) | HTPA reductase |
| 2 | B (A) | PYRIDINE-2,6-DICARBOXYLIC ACID | non-polymer | 167.1 | 1 | Chemie (PDC) PubChem (10367) | |||
| 3 | C (A) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (11250888) PubChem (12309341) PubChem (94865921) PubChem (94865923) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (124432988) PubChem (12309347) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (146167236) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (162951602) PubChem (174084875) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | BENZOIC ACID | non-polymer | 122.1 | 1 | Chemie (BEZ) | |||
| 6 | F (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 7 | G (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 8 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 9 | I, J, K, L, M... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 10 | O (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 11 | P (A) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 1 - 244 (UniProt: A5U6C6)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25682.3 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1744.9 | |
| All* | Total formula weight | 27427.2 |
