5TJX
Structure of human plasma kallikrein
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Plasma kallikrein | polymer | 263 | 29427.3 | 1 | UniProt (P03952) Pfam (PF00089) In PDB | Homo sapiens (Human) | Fletcher factor,Kininogenin,Plasma prekallikrein,PKK |
2 | A | (8E)-3-amino-1-methyl-15-[(1H-pyrazol-1-yl)methyl]-7,10,11,12,24,25-hexahydro-6H,18H,23H-19,22-(metheno)pyrido[4,3-j][1,9,13,17,18]benzodioxatriazacyclohenicosin-23-one | non-polymer | 527.6 | 1 | Chemie (GBT) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
A: 376 - 638 (UniProt: P03952)
PDB | External Database | Details |
---|---|---|
Glu 396 | Asn 396 | engineered mutation |
Glu 453 | Asn 453 | engineered mutation |
Glu 494 | Asn 494 | engineered mutation |
Ser 503 | Cys 503 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29427.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 717.6 | |
All* | Total formula weight | 30144.9 |