5TJX
Structure of human plasma kallikrein
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue GBT A 701 |
| Chain | Residue |
| A | HIS434 |
| A | SER578 |
| A | THR596 |
| A | SER597 |
| A | TRP598 |
| A | GLY599 |
| A | GLY601 |
| A | CYS602 |
| A | PO4702 |
| A | HOH846 |
| A | HOH896 |
| A | SER478 |
| A | HOH897 |
| A | HOH947 |
| A | GLU479 |
| A | GLY480 |
| A | TYR555 |
| A | MET561 |
| A | ASP572 |
| A | ALA573 |
| A | CYS574 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 702 |
| Chain | Residue |
| A | LEU418 |
| A | HIS434 |
| A | LYS575 |
| A | GLY576 |
| A | SER578 |
| A | GBT701 |
| A | HOH811 |
| A | HOH816 |
| A | HOH823 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 703 |
| Chain | Residue |
| A | HIS472 |
| A | GLN473 |
| A | ARG560 |
| A | HOH955 |
| A | HOH957 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU430-CYS435 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLV |
| Chain | Residue | Details |
| A | ASP572-VAL583 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3521732","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3521732","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
