5TIB

Gasdermin-B C-terminal domain containing the polymorphism residues Arg299:Ser306 fused to maltose binding protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Sugar ABC transporter substrate-binding protein,Gasdermin-B	polymer	557	61086.2	2	UniProt (A0A178SBV6) UniProt (Q8TAX9) Pfam (PF17708) In PDB	Escherichia coli Homo sapiens (Human)	Gasdermin-like protein
2	C, D	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	2	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose
3	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5		water	water		18.0	286	Chemie (HOH)

Sequence modifications

A, B: 1 - 366 (UniProt: A0A178SBV6)

PDB	External Database	Details
Ala 82	Asp 108	see remark 999
Ala 83	Lys 109	see remark 999
Ala 172	Glu 198	see remark 999
Ala 173	Asn 199	see remark 999
Ala 239	Lys 265	see remark 999
Ala 362	Lys 388	see remark 999
Ala 363	Asp 389	see remark 999
Asn 367	-	linker
Ala 368	-	linker
Ala 369	-	linker
Ala 370	-	linker

A, B: 1220 - 1406 (UniProt: Q8TAX9)

PDB	External Database	Details
Arg 1299	Gly 299	see remark 999
Ser 1306	Pro 306	see remark 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122172.5
Branched	Number of molecules	2
	Total formula weight	684.6
Non-Polymers*	Number of molecules	2
	Total formula weight	82.0
All*	Total formula weight	122939.1

*Water molecules are not included.