5THF
Crystal structure of H3 hemagglutinin with insertion of two amino acids in the 150-loop from the A/Hong Kong/1/1968 (H3N2) influenza virus
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Hemagglutinin HA1 chain | polymer | 325 | 35723.2 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
2 | B, D, F | Hemagglutinin HA2 chain | polymer | 184 | 20854.9 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus | |
3 | G, I, K | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
4 | H, J, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
5 | A, C, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
6 | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: Q91MA7)
B, D, F: 1 - 176 (UniProt: Q91MA7)
PDB | External Database | Details |
---|---|---|
Ala 7 | - | expression tag |
Asp 8 | - | expression tag |
Pro 9 | - | expression tag |
Gly 10 | - | expression tag |
Ser 157 | - | insertion |
Lys 157 | - | insertion |
PDB | External Database | Details |
---|---|---|
Gly 123 | Arg 468 | engineered mutation |
Ser 177 | - | expression tag |
Gly 178 | - | expression tag |
Gly 179 | - | expression tag |
Gly 180 | - | expression tag |
Gly 181 | - | expression tag |
Leu 182 | - | expression tag |
Asn 183 | - | expression tag |
Asp 184 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 169734.4 | |
Branched | Number of molecules | 6 |
Total formula weight | 3032.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 884.8 | |
All* | Total formula weight | 173652.1 |