5TFN
CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS2B-NS3 PROTEASE in super-open conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NS2B-NS3 Protease CHIMERA,Genome polyprotein | polymer | 241 | 25512.4 | 2 | UniProt (A0A160JCU6) UniProt (Q32ZE1) Pfam (PF01002) Pfam (PF00949) | Zika virus (ZIKV) | |
| 2 | C, D (A, B) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B: 48 - 94 (UniProt: A0A160JCU6)
A, B: 1001 - 1182 (UniProt: Q32ZE1)
| PDB | External Database | Details |
|---|---|---|
| Gly 46 | - | expression tag |
| Ser 47 | - | expression tag |
| Ala 95 | - | linker |
| Gly 96 | - | linker |
| Gly 97 | - | linker |
| Gly 98 | - | linker |
| Gly 99 | - | linker |
| Ser 100 | - | linker |
| Gly 101 | - | linker |
| Gly 102 | - | linker |
| Gly 103 | - | linker |
| Gly 104 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 1056 | Ala 1554 | engineered mutation |
| His 1092 | Leu 1590 | conflict |
| Ala 1135 | Ser 1633 | conflict |
| Arg 1169 | Lys 1667 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51024.8 | |
| All* | Total formula weight | 51024.8 |
