5TDZ
TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-citrate synthase | polymer | 431 | 47836.6 | 1 | UniProt (P53396) Pfam (PF24948) Pfam (PF16114) | Homo sapiens (Human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
| 2 | B (B) | ATP-citrate synthase | polymer | 324 | 35421.6 | 1 | UniProt (P53396) Pfam (PF02629) Pfam (PF00549) | Homo sapiens (Human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
| 3 | C (A) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TLA) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | G (A) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 8 | H, K (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | I, L (A, B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 10 | J (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 11 | M, N (A, B) | water | water | 18.0 | 506 | Chemie (HOH) |
Sequence modifications
A: 1 - 425 (UniProt: P53396)
B: 488 - 810 (UniProt: P53396)
| PDB | External Database | Details |
|---|---|---|
| Glu 426 | - | SEE REMARK 999 |
| Asn 427 | - | SEE REMARK 999 |
| Leu 428 | - | SEE REMARK 999 |
| Tyr 429 | - | SEE REMARK 999 |
| Phe 430 | - | SEE REMARK 999 |
| Gln 431 | - | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Ser 487 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83258.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1570.5 | |
| All* | Total formula weight | 84828.7 |
