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5TDA

Crystal structure of the UBR-box domain from UBR2 in complex with RLWS N-degron

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase UBR2polymer768350.51UniProt (Q8IWV8)
Pfam (PF02207)
Homo sapiens (Human)N-recognin-2,Ubiquitin-protein ligase E3-alpha-2,Ubiquitin-protein ligase E3-alpha-II
2B
(B)
ARG-LEU-TRP-SER peptidepolymer4561.71Homo sapiens
3C, D, E
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
4F, G
(A, B)
waterwater18.0107Chemie (HOH)
Sequence modifications
A: 98 - 168 (UniProt: Q8IWV8)
PDBExternal DatabaseDetails
Gly 93-expression tag
Pro 94-expression tag
Leu 95-expression tag
Gly 96-expression tag
Ser 97-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight8912.2
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight9108.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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