5TCM
First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Uncharacterized protein | polymer | 130 | 14655.3 | 3 | UniProt (E9BA17) Pfam (PF00439) UniProt (by SIFTS) (A0A3Q8I8I6) In PDB | Leishmania donovani (strain BPK282A1) | |
2 | A, B, C | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 521.7 | 3 | Chemie (R78) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
4 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, B, C: 5 - 116 (UniProt: E9BA17)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
Ser -6 | - | expression tag |
Ser -5 | - | expression tag |
Gly -4 | - | expression tag |
Arg -3 | - | expression tag |
Glu -2 | - | expression tag |
Asn -1 | - | expression tag |
Leu 0 | - | expression tag |
Tyr 1 | - | expression tag |
Phe 2 | - | expression tag |
Gln 3 | - | expression tag |
Gly 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 43965.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1751.2 | |
All* | Total formula weight | 45716.9 |