5TCA

Complement Factor D inhibited with JH3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Complement factor D	polymer	228	24438.8	7	UniProt (P00746) Pfam (PF00089)	Homo sapiens (Human)	Adipsin,C3 convertase activator,Properdin factor D
2	H, I, J, K, L... (A, B, C, D, E...)	1-(2-{(2S)-2-[(6-bromopyridin-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide	non-polymer		490.3	9	Chemie (J55)
3	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	93	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	171071.6
Non-Polymers*	Number of molecules	9
	Total formula weight	4413.0
All*	Total formula weight	175484.7

*Water molecules are not included.