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5TB9

Precatalytic ternary complex of Human DNA Polymerase Beta in closed conformation With Gapped DNA substrate incoming (-)FTC-TP and Mn2+.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase betapolymer34339258.81UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)
2D5-MER PHOSPHORYLATED DOWNSTREAM PRIMERpolymer51536.01Synthetic construct
3P10- MER PRIMERpolymer103061.01Synthetic construct
4T16- MER TEMPLATEpolymer164869.21Synthetic construct
5A[[(2R,5S)-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphatenon-polymer487.21Chemie (1RY)
6AMANGANESE (II) IONnon-polymer54.96Chemie (MN)
7A, PSODIUM IONnon-polymer23.04Chemie (NA)
8A, TACETATE IONnon-polymer59.03Chemie (ACT)
9waterwater18.074Chemie (HOH)
Sequence modifications
A: 1 - 335 (UniProt: P06746)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Gly 0-expression tag
His 336-expression tag
His 337-expression tag
His 338-expression tag
His 339-expression tag
His 340-expression tag
His 341-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight48725.0
Non-Polymers*Number of molecules14
Total formula weight1085.9
All*Total formula weight49810.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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