5T8S
Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound S-adenosylmethionine, AMP, Pyrophosphate, Phosphate, and Magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | S-adenosylmethionine synthase | polymer | 397 | 43017.5 | 2 | UniProt (Q5FAC0) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) | AdoMet synthase,MAT,Methionine adenosyltransferase |
| 2 | C, E, H, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | D (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 4 | F (A) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 5 | G (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | I (B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 7 | K (B) | TRIPHOSPHATE | non-polymer | 258.0 | 1 | Chemie (3PO) | |||
| 8 | L, M (A, B) | water | water | 18.0 | 688 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 389 (UniProt: Q5FAC0)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86035.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1371.8 | |
| All* | Total formula weight | 87406.7 |
