5T4V
Crystal structure of the bromodomain of human BRPF1 in complex with NI-48 ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peregrin | polymer | 116 | 13703.7 | 1 | UniProt (P55201) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
| 2 | A | 4-cyano-N-(7-methoxy-1,4-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)benzene-1-sulfonamide | non-polymer | 383.4 | 1 | Chemie (N48) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 5 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 627 - 740 (UniProt: P55201)
| PDB | External Database | Details |
|---|---|---|
| Ser 625 | - | expression tag |
| Met 626 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13703.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 491.5 | |
| All* | Total formula weight | 14195.2 |
