5T4V
Crystal structure of the bromodomain of human BRPF1 in complex with NI-48 ligand
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue N48 A 801 |
| Chain | Residue |
| A | ARG638 |
| A | HOH908 |
| A | HOH950 |
| A | LYS639 |
| A | GLU642 |
| A | VAL657 |
| A | PRO658 |
| A | GLU661 |
| A | CYS704 |
| A | ASN708 |
| A | PHE714 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 802 |
| Chain | Residue |
| A | LYS706 |
| A | TYR707 |
| A | ALA709 |
| A | LYS710 |
| A | HOH956 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 803 |
| Chain | Residue |
| A | GLN680 |
| A | GLN680 |
| A | ARG686 |
| A | ARG686 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
