5T4U
Crystal structure of the bromodomain of human BRPF1 in complex with a quinolinone ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peregrin | polymer | 116 | 13703.7 | 1 | UniProt (P55201) Pfam (PF00439) | Homo sapiens (Human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
| 2 | B (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 3 | C (A) | 1-METHYLQUINOLIN-2(1H)-ONE | non-polymer | 159.2 | 1 | Chemie (12Q) | |||
| 4 | D (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 627 - 740 (UniProt: P55201)
| PDB | External Database | Details |
|---|---|---|
| Ser 625 | - | expression tag |
| Met 626 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13703.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 13924.9 |
