5T4N

Crystal Structure of Human Protocadherin-15 EC3-5 D414A Variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protocadherin-15	polymer	365	40836.7	2	UniProt (Q96QU1) Pfam (PF00028)	Homo sapiens (Human)
2	C, D, E, F, G... (A, B)	CALCIUM ION	non-polymer		40.1	10	Chemie (CA)
3	M (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	N, O (A, B)	water	water		18.0	262	Chemie (HOH)

Sequence modifications

A, B: 242 - 595 (UniProt: Q96QU1)

PDB	External Database	Details
Met 239	-	initiating methionine
Ala 240	-	expression tag
Ser 241	-	expression tag
Ala 414	Asp 435	engineered mutation
Leu 596	-	expression tag
Glu 597	-	expression tag
His 598	-	expression tag
His 599	-	expression tag
His 600	-	expression tag
His 601	-	expression tag
His 602	-	expression tag
His 603	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	81673.5
Non-Polymers*	Number of molecules	11
	Total formula weight	436.2
All*	Total formula weight	82109.7

*Water molecules are not included.