5T48

Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Eukaryotic translation initiation factor 4E	polymer	184	21249.0	1	UniProt (P48598) Pfam (PF01652) In PDB	Drosophila melanogaster (Fruit fly)	eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein
2	B	Eukaryotic translation initiation factor 4G, isoform A	polymer	64	7410.4	1	UniProt (O61380) Pfam (PF21140) In PDB	Drosophila melanogaster (Fruit fly)	Eukaryotic translation initiation factor 4G,isoform C,FI02056p,Translation initiation factor eIF4G
3	A	7-METHYL-GUANOSINE-5'-TRIPHOSPHATE	non-polymer		538.2	1	Chemie (MGP)
4		water	water		18.0	35	Chemie (HOH)

Sequence modifications

A: 69 - 248 (UniProt: P48598)

PDB	External Database	Details
Gly 65	-	expression tag
Pro 66	-	expression tag
His 67	-	expression tag
Met 68	-	expression tag

B: 601 - 660 (UniProt: O61380)

PDB	External Database	Details
Gly 597	-	expression tag
Pro 598	-	expression tag
His 599	-	expression tag
Met 600	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28659.4
Non-Polymers*	Number of molecules	1
	Total formula weight	538.2
All*	Total formula weight	29197.6

*Water molecules are not included.