5T3N

Sp-2Cl-cAMPS bound to PKAR CBD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	cAMP-dependent protein kinase regulatory subunit	polymer	161	18511.2	2	UniProt (Q7KQK0) Pfam (PF00027) In PDB	Plasmodium falciparum (isolate 3D7)
2	A, B	IODIDE ION	non-polymer		126.9	5	Chemie (IOD)
3	A, B	(2S,4aR,6R,7R,7aS)-6-(6-amino-2-chloro-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one	non-polymer		379.7	2	Chemie (75G)
4		water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B: 297 - 441 (UniProt: Q7KQK0)

PDB	External Database	Details
Met 281	-	initiating methionine
Ala 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag
His 286	-	expression tag
His 287	-	expression tag
His 288	-	expression tag
Glu 289	-	expression tag
Val 290	-	expression tag
Leu 291	-	expression tag
Phe 292	-	expression tag
Gln 293	-	expression tag
Gly 294	-	expression tag
Pro 295	-	expression tag
Gly 296	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37022.5
Non-Polymers*	Number of molecules	7
	Total formula weight	1394.0
All*	Total formula weight	38416.4

*Water molecules are not included.