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5T33

Crystal structure of strain-specific glycan-dependent CD4 binding site-directed neutralizing antibody CAP257-RH1, in complex with HIV-1 strain RHPA gp120 core with an oligomannose N276 glycan.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1HCAP257-RH1 heavy chainpolymer22323888.91Homo sapiens
2LCAP257-RH1 light chainpolymer21422957.41Homo sapiens
3GRHPA gp120 corepolymer35739997.21Human immunodeficiency virus
4A, D2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
5Balpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G22573RC)
6Calpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1235.11In PDB
GlyTouCan (G55220VL)
7G2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.26Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight86843.5
BranchedNumber of molecules4
Total formula weight2832.6
Non-Polymers*Number of molecules6
Total formula weight1327.2
All*Total formula weight91003.3
*Water molecules are not included.

220113

PDB entries from 2024-05-22

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