5T2H
Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | I-OnuI_e-hTCRa | polymer | 299 | 34775.3 | 1 | synthetic construct | ||
| 2 | B (B) | DNA (26-MER) | polymer | 26 | 7976.1 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (26-MER) | polymer | 26 | 7999.2 | 1 | synthetic construct | ||
| 4 | D, E (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F, G, H (A, B, C) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50750.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 50830.7 |
