5T2H
Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004519 | molecular_function | endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | ALA21 |
| A | GLU178 |
| A | HOH504 |
| B | DC14 |
| C | DA16 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| B | DA15 |
| C | DT15 |
| A | GLU22 |
| A | GLY177 |
| A | HOH515 |
| A | HOH519 |
