5T1V

Crystal structure of Zika virus NS2B-NS3 protease in apo-form.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NS2B-NS3 protease,NS2B-NS3 protease	polymer	273	29072.8	2	UniProt (Q32ZE1) Pfam (PF01002) Pfam (PF00949)	Zika virus (ZIKV)

Sequence modifications

A, B: 3 - 56 (UniProt: Q32ZE1)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Ala -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Gly 1	-	expression tag
Pro 2	-	expression tag

A, B: 66 - 252 (UniProt: Q32ZE1)

PDB	External Database	Details
Gly 57	-	linker
Gly 58	-	linker
Gly 59	-	linker
Gly 60	-	linker
Ser 61	-	linker
Gly 62	-	linker
Gly 63	-	linker
Gly 64	-	linker
Gly 65	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58145.5
All*	Total formula weight	58145.5

*Water molecules are not included.