5SY5

Crystal Structure of the Heterodimeric NPAS1-ARNT Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	Aryl hydrocarbon receptor nuclear translocator	polymer	384	43437.4	3	UniProt (P53762) Pfam (PF00010) Pfam (PF00989) Pfam (PF14598) In PDB	Mus musculus (Mouse)	ARNT protein,Dioxin receptor,nuclear translocator,Hypoxia-inducible factor 1-beta,HIF1-beta
2	B, D, F	Neuronal PAS domain-containing protein 1	polymer	391	42659.6	3	UniProt (P97459) Pfam (PF00010) Pfam (PF00989) Pfam (PF08447) In PDB	Mus musculus (Mouse)	Neuronal PAS1

Sequence modifications

A, C, E: 82 - 464 (UniProt: P53762)

PDB	External Database	Details
Met 81	-	initiating methionine

B, D, F: 43 - 423 (UniProt: P97459)

PDB	External Database	Details
Met 41	-	initiating methionine
Ile 42	-	expression tag
Leu 424	-	expression tag
Glu 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	258291.0
All*	Total formula weight	258291.0

*Water molecules are not included.