5SXP
STRUCTURAL BASIS FOR THE INTERACTION BETWEEN ITCH PRR AND BETA-PIX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Rho guanine nucleotide exchange factor 7 | polymer | 62 | 7094.7 | 4 | UniProt (Q14155) Pfam (PF07653) | Homo sapiens (Human) | Beta-Pix,COOL-1,PAK-interacting exchange factor beta,p85 |
| 2 | E, F (F, G) | E3 ubiquitin-protein ligase Itchy homolog | polymer | 27 | 2816.2 | 2 | UniProt (Q96J02) | Homo sapiens (Human) | Itch,Atrophin-1-interacting protein 4,AIP4,NFE2-associated polypeptide 1,NAPP1 |
| 3 | G, H, I, J, K... (A, B, C, D, F...) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 183 - 243 (UniProt: Q14155)
F, G: 249 - 269 (UniProt: Q96J02)
| PDB | External Database | Details |
|---|---|---|
| Gly 182 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 244 | - | expression tag |
| Ser 245 | - | expression tag |
| Gly 246 | - | expression tag |
| Gly 247 | - | expression tag |
| Gly 248 | - | expression tag |
| Tyr 270 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 34011.3 | |
| All* | Total formula weight | 34011.3 |
