5SWW
Crystal Structure of Human APOBEC3A complexed with ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DNA dC->dU-editing enzyme APOBEC-3A | polymer | 204 | 23468.6 | 4 | UniProt (P31941) Pfam (PF05240) | Homo sapiens (Human) | A3A,Phorbolin-1 |
| 2 | E, F, G, H (E, F, G, H) | DNA 15-Mer | polymer | 15 | 4668.1 | 4 | Homo sapiens | ||
| 3 | I, J, M, N (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | K, L, O, P (B, E, F) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 196 (UniProt: P31941)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Ala 72 | Glu 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 112546.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 630.0 | |
| All* | Total formula weight | 113176.6 |
