5SVL
Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, closed (desensitized) state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | P2X purinoceptor 3 | polymer | 363 | 40723.8 | 2 | UniProt (P56373) Pfam (PF00864) | Homo sapiens (Human) | P2X3,ATP receptor,Purinergic receptor |
| 2 | C (C) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
| 3 | D, Q (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | E, F, G, R, S... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 5 | H, I, J, K, U... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | L, M, W (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 7 | N, O, X (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 8 | P (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 9 | Y, Z (A, B) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 364 (UniProt: P56373)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Ala 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81447.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3082.3 | |
| All* | Total formula weight | 84872.2 |
