5SVH
Crystal structure of the KIX domain of CBP in complex with a MLL/c-Myb chimera
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CREB-binding protein | polymer | 87 | 10353.9 | 1 | UniProt (Q92793) Pfam (PF02172) | Homo sapiens (Human) | |
| 2 | B (B) | MLL/c-Myb chimera | polymer | 58 | 6383.2 | 1 | UniProt (Q03164) UniProt (P01103) Pfam (PF07988) | Homo sapiens (Human) | Lysine N-methyltransferase 2A,ALL-1,CXXC-type zinc finger protein 7,Myeloid/lymphoid or mixed-lineage leukemia,Myeloid/lymphoid or mixed-lineage leukemia protein 1,Trithorax-like protein,Zinc finger protein HRX,Proto-oncogene c-Myb |
| 3 | C, I (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | D, E, F, G, H... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
B: 1 - 31 (UniProt: Q03164)
B: 32 - 56 (UniProt: P01103)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ser 1 | Asp 2839 | conflict |
| Asp 3 | Cys 2841 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16737.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 432.4 | |
| All* | Total formula weight | 17169.4 |
