5SAY

DDR1, N-[2-[3-(2-aminopyrimidin-5-yl)oxyphenyl]ethyl]-3-(trifluoromethoxy)benzamide, 2.190A, P1211, Rfree=27.7%

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Epithelial discoidin domain-containing receptor 1	polymer	321	36502.9	2	UniProt (Q08345) Pfam (PF07714) In PDB	Homo sapiens (Human)	Epithelial discoidin domain receptor 1,CD167 antigen-like family member A,Cell adhesion kinase,Discoidin receptor tyrosine kinase,HGK2,Mammary carcinoma kinase 10,MCK-10,Protein-tyrosine kinase 3A,Protein-tyrosine kinase RTK-6,TRK E,Tyrosine kinase DDR,Tyrosine-protein kinase CAK
2	A, B	IODIDE ION	non-polymer		126.9	15	Chemie (IOD)
3	A, B	N-(2-{3-[(2-aminopyrimidin-5-yl)oxy]phenyl}ethyl)-3-(trifluoromethoxy)benzamide	non-polymer		418.4	2	Chemie (1IJ)
4		water	water		18.0	180	Chemie (HOH)

Sequence modifications

A, B: 593 - 907 (UniProt: Q08345)

PDB	External Database	Details
-	Gly 730	deletion
-	Gln 731	deletion
-	Ala 732	deletion
-	Ala 733	deletion
-	Gln 734	deletion
-	Gly 735	deletion
His 908	-	expression tag
His 909	-	expression tag
His 910	-	expression tag
His 911	-	expression tag
His 912	-	expression tag
His 913	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73005.7
Non-Polymers*	Number of molecules	17
	Total formula weight	2740.3
All*	Total formula weight	75746.0

*Water molecules are not included.