5R4T
PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with SK-430
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cleavage and polyadenylation specificity factor subunit 5 | polymer | 197 | 22874.4 | 2 | UniProt (O43809) Pfam (PF13869) | Homo sapiens (Human) | Cleavage and polyadenylation specificity factor 25 kDa subunit,CPSF 25 kDa subunit,Cleavage factor Im complex 25 kDa subunit,CFIm25,Nucleoside diphosphate-linked moiety X motif 21,Nudix motif 21,Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit |
| 2 | C, D, I, J, K... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | E, F, M (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | G, H (A) | (5R)-5-{[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]methyl}-5-methylpyrrolidine-2,4-dione | non-polymer | 288.3 | 2 | Chemie (RWG) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 227 (UniProt: O43809)
| PDB | External Database | Details |
|---|---|---|
| Ser 31 | - | expression tag |
| Met 32 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45748.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1146.1 | |
| All* | Total formula weight | 46894.9 |
