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5QOY

PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with YW-FY-378

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DCP2 (NUDT20)polymer16719073.71UniProt (Q8IU60)
Pfam (PF00293)
Homo sapiens (Human)Nucleoside diphosphate-linked moiety X motif 20, Nudix motif 20, mRNA-decapping enzyme 2, hDpc, m7GpppN-mRNA hydrolase
2B, C
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
3D
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
4E, F
(A)
ACETATE IONnon-polymer59.02Chemie (ACT)
5G
(A)
1-[4-(2H-1,3-benzodioxole-5-carbonyl)-2,3,4,5-tetrahydro-1H-1,4-diazepin-1-yl]ethan-1-onenon-polymer288.31Chemie (LFJ)
6H
(A)
waterwater18.088Chemie (HOH)
Sequence modifications
A: 95 - 260 (UniProt: Q8IU60)
PDBExternal DatabaseDetails
Ser 94-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19073.7
Non-Polymers*Number of molecules6
Total formula weight608.7
All*Total formula weight19682.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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