5Q1A
Ligand binding to FARNESOID-X-RECEPTOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Bile acid receptor | polymer | 233 | 27100.2 | 2 | UniProt (Q96RI1) Pfam (PF00104) In PDB | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
2 | B, D | COACTIVATOR PEPTIDE SRC-1 HD3 | polymer | 14 | 1790.0 | 2 | UniProt (A8K1V4) UniProt (by SIFTS) (Q15788) In PDB | Homo sapiens | |
3 | A, C | (2S)-2-cyclohexyl-2-[2-(2,4-dimethoxyphenyl)-1H-benzimidazol-1-yl]-N-(2,6-dimethylphenyl)acetamide | non-polymer | 497.6 | 2 | Chemie (9N4) | |||
4 | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A, C: 248 - 476 (UniProt: Q96RI1)
PDB | External Database | Details |
---|---|---|
Gly 244 | - | expression tag |
Ser 245 | - | expression tag |
His 246 | - | expression tag |
Met 247 | - | expression tag |
Ala 281 | Glu 291 | conflict |
Ala 354 | Glu 364 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 57780.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 995.3 | |
All* | Total formula weight | 58775.7 |