Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032052 | molecular_function | bile acid binding |
| A | 0038183 | biological_process | bile acid signaling pathway |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0032052 | molecular_function | bile acid binding |
| C | 0038183 | biological_process | bile acid signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 9N4 A 501 |
| Chain | Residue |
| A | ILE273 |
| A | ILE356 |
| A | SER359 |
| A | ILE361 |
| A | MET369 |
| A | TYR373 |
| A | HIS451 |
| A | MET454 |
| A | LEU455 |
| A | TRP458 |
| A | ILE277 |
| A | ASN287 |
| A | LEU291 |
| A | MET294 |
| A | HIS298 |
| A | MET332 |
| A | PHE333 |
| A | SER336 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue 9N4 C 501 |
| Chain | Residue |
| C | ILE277 |
| C | ASN287 |
| C | LEU291 |
| C | MET294 |
| C | HIS298 |
| C | MET332 |
| C | PHE333 |
| C | SER336 |
| C | ILE356 |
| C | SER359 |
| C | ILE361 |
| C | MET369 |
| C | TYR373 |
| C | HIS451 |
| C | TRP458 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 224 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"6HL1","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC/PRKCZ","evidences":[{"source":"PubMed","id":"18668687","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"23546875","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 5"} |
