5Q0X
Ligand binding to FARNESOID-X-RECEPTOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bile acid receptor | polymer | 233 | 27100.2 | 1 | UniProt (Q96RI1) Pfam (PF00104) In PDB | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
2 | B | COACTIVATOR PEPTIDE SRC-1 HD3 | polymer | 14 | 1790.0 | 1 | UniProt (A8K1V4) UniProt (by SIFTS) (Q15788) In PDB | Homo sapiens | |
3 | A | 6-(4-{[3-(3,5-dichloropyridin-4-yl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-2-methylphenyl)-1-methyl-1H-indole-3-carbox ylic acid | non-polymer | 550.4 | 1 | Chemie (643) | |||
4 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 248 - 476 (UniProt: Q96RI1)
PDB | External Database | Details |
---|---|---|
Gly 244 | - | expression tag |
Ser 245 | - | expression tag |
His 246 | - | expression tag |
Met 247 | - | expression tag |
Ala 281 | Glu 291 | conflict |
Ala 354 | Glu 364 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28890.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 550.4 | |
All* | Total formula weight | 29440.6 |