5PZW
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[5-[(3-chlorophenyl)sulfonylcarbamoylamino]pentyl]urea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36859.4 | 4 | UniProt (Q2TU34) Pfam (PF00316) Pfam (PF18913) UniProt (by SIFTS) (P09467) | Homo sapiens (Human) | Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA |
| 2 | E, G (A, B) | N,N'-(pentane-1,5-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide) | non-polymer | 537.4 | 2 | Chemie (94J) PubChem (24968299) | |||
| 3 | F, H (A, D) | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | non-polymer | 338.2 | 2 | Chemie (AMZ) PubChem (16760280) PubChem (25322835) PubChem (29971658) PubChem (29971663) PubChem (46874858) PubChem (46936194) PubChem (69015652) PubChem (200) PubChem (65110) PubChem (90004537) PubChem (92209412) PubChem (92209413) PubChem (92209414) PubChem (92209415) PubChem (159841653) PubChem (162938701) PubChem (163812830) PubChem (171699377) PubChem (173757272) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1452 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147437.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1751.3 | |
| All* | Total formula weight | 149189.0 |
