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5PZW

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[5-[(3-chlorophenyl)sulfonylcarbamoylamino]pentyl]urea

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Fructose-1,6-bisphosphatase 1polymer33836859.44UniProt (Q2TU34)
Pfam (PF00316)
Pfam (PF18913)
UniProt (by SIFTS) (P09467)
Homo sapiens (Human)Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
2E, G
(A, B)
N,N'-(pentane-1,5-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide)non-polymer537.42Chemie (94J)
3F, H
(A, D)
AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDEnon-polymer338.22Chemie (AMZ)
4I, J, K, L
(A, B, C, D)
waterwater18.01452Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight147437.7
Non-Polymers*Number of molecules4
Total formula weight1751.3
All*Total formula weight149189.0
*Water molecules are not included.

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PDB entries from 2026-02-18

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