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5PZV

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromopyridin-2-yl)-3-(4-chlorophenyl)sulfonylurea

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Fructose-1,6-bisphosphatase 1polymer33836859.44UniProt (Q2TU34)
Pfam (PF00316)
Pfam (PF18913)
UniProt (by SIFTS) (P09467)
Homo sapiens (Human)Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
2E, F, G, H
(A, B, C, D)
N-[(4-bromopyridin-2-yl)carbamoyl]-4-chlorobenzene-1-sulfonamidenon-polymer390.64Chemie (94G)
3I, J, K, L
(A, B, C, D)
waterwater18.01002Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight147437.7
Non-Polymers*Number of molecules4
Total formula weight1562.6
All*Total formula weight149000.2
*Water molecules are not included.

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PDB entries from 2026-01-14

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