5PAV
Crystal Structure of Factor VIIa in complex with N-(6-aminopyridin-3-yl)-5-hydroxy-1-phenylpyrazole-4-carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor VII light chain | polymer | 64 | 6984.9 | 1 | UniProt (P08709) Pfam (PF14670) | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 2 | B (C) | Coagulation factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | C, J (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | D, E, K, L, M (A, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | F (C) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | G, H, I (C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | N (C) | N-(6-aminopyridin-3-yl)-5-hydroxy-1-phenylpyrazole-4-carboxamide | non-polymer | 295.3 | 1 | Chemie (7ZM) | |||
| 8 | O, P (A, C) | water | water | 18.0 | 446 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35088.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1094.3 | |
| All* | Total formula weight | 36182.5 |
